HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphoric Acid → 3-(2',4'-Difluoro-4-biphenylyl)butyric acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphoric Acid | HCID 1004 | — |
| Reactant | Potassium Iodide | HCID 4875 | — |
| Reactant | 3-(2',4'-Difluoro-4-biphenylyl)-3-hydroxybutyric acid ethyl ester | HCID 53834251 | — |
| Product | 3-(2',4'-Difluoro-4-biphenylyl)butyric acid ethyl ester | HCID 54340187 | — |
Reaction Steps
A mixture of 32 g. of 3-(2',4'-difluoro-4-biphenylyl)-3-hydroxybutyric acid ethyl ester, 8.7 g. of potassium iodide, 5.2 g. of red phosphorus and 45 ml. of 85% phosphoric acid is stirred and heated to 130° for 7 hours. It is worked up in the customary manner to give 3-(2',4'-difluoro-4-biphenylyl)butyric acid ethyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04151302 |
| Source dataset | uspto-grants-1979_04 |
| ORD ID | ord-085bc1f8311845d093222f9e2ed74cd1 |
| Source note | uspto-grants-1979_04 |