Sodium Hydroxide → HCID 21322546, compound

HRID 26910Notes

Reaction equation

HRID 26910 reaction equation
C([O:3][C:4](=[O:23])[CH2:5][C:6]([C:9]1[CH:14]=[CH:13][C:12]([C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[C:17]([Cl:22])[CH:16]=2)=[CH:11][CH:10]=1)([OH:8])[CH3:7])C.[OH-].[Na+]>C(O)(C)C>[Cl:22][C:17]1[CH:16]=[C:15]([C:12]2[CH:11]=[CH:10][C:9]([C:6]([OH:8])([CH3:7])[CH2:5][C:4]([OH:23])=[O:3])=[CH:14][CH:13]=2)[CH:20]=[CH:19][C:18]=1[Cl:21]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 544122843-(3',4'-Dichloro-4-biphenylyl)-3-hydroxybutyric acid ethyl ester

Product 1

HCID 21322546HCID 21322546, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

1 g. of 3-(3',4'-dichloro-4-biphenylyl)-3-hydroxybutyric acid ethyl ester and 0.2 g. of NaOH in 40 ml. of isopropanol are left to stand for 24 hours and the mixture is worked up to give 3-(3',4'-dichloro-4-biphenylyl)-3-hydroxybutyric acid, m.p. 124°-126°.

Sources & evidence

ORD record
ord-a1f6b2f2b1ed4bc6881dc90e9cffc798
Source dataset
uspto-grants-1979_04
Patent number
US04151302

Reaction notes

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