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HRID269172

反应详情

EQUATION

反应方程式

HRID 269172 的结构方程式

REACTANTS

反应物

2
结构：NS(=O)(=O)c1ccc(Br)s1
HCID1241304

5-Bromothiophene-2-sulfonamide

C4H4BrNO2S2

结构：C#Cc1cnn2c(C(F)(F)F)cc(-c3ccc(Cl)cc3)nc12
HCID86607995

未命名化合物

PRODUCTS

生成物

1
结构：NS(=O)(=O)c1ccc(C#Cc2cnn3c(C(F)(F)F)cc(-c4ccc(Cl)cc4)nc23)s1
HCID67001359

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 5-(4-chloro-phenyl)-3-ethynyl-7-trifluoromethyl pyrazolo[1,5-a]pyrimidine (example C.4) (322 mg, 1.0 mmol) and 5-bromo-thiophene-2-sulfonic acid amide (242 mg, 1.0 mmol) according to general procedure II. Obtained as a yellow solid (247 mg, 51%). MS (ISP) 483.5 [(M+H)+]; mp 239-240° C.