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HRID269176

反应详情

EQUATION

反应方程式

HRID 269176 的结构方程式

REACTANTS

反应物

2
结构：Brc1cccnc1
HCID12286

3-Bromopyridine

C5H4BrN

结构：C#Cc1cnn2c(C(F)(F)F)cc(-c3ccc(Cl)c(C)c3)nc12
HCID86608053

未命名化合物

PRODUCTS

生成物

1
结构：Cc1cc(-c2cc(C(F)(F)F)n3ncc(C#Cc4cccnc4)c3n2)ccc1Cl
HCID67000907

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 5-(4-chloro-3-methyl-phenyl)-3-ethynyl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine (example C.11) (336 mg, 1.0 mmol) and commercially available 3-bromopyridine (158 mg, 1.0 mmol) according to general procedure II. Obtained as a yellow solid (90 mg, 22%). MS (ISP) 413.0 [(M+H)+]; mp 196° C.