HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Iodo-3-(trifluoromethyl)pyridin-2-amine → HCID 86608102, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Iodo-3-(trifluoromethyl)pyridin-2-amine | HCID 58235306 | — |
| Reactant | 5-(4-Chloro-phenyl)-3-ethynyl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine | HCID 86607995 | — |
| Product | HCID 86608102 | HCID 86608102 | — |
Reaction Steps
The title compound was prepared from 5-(4-chloro-phenyl)-3-ethynyl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine (example C.4) (322 g, 1.0 mmol) and 5-iodo-3-trifluoromethyl-pyridin-2-ylamine (example B.48) (288 mg, 1.0 mmol) according to general procedure II. Obtained as an orange solid (290 mg, 60%). MS (ISP) 482.3 [(M+H)+], 484 [(M+2+H)+]; mp 209° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07446113B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-169c72ecbee04562a3ca4595ca69d064 |
| Source note | uspto-grants-2008_11 |