反应详情

A mixture of 1 g. of 3-(2',4'-difluoro-4-biphenylyl)butyramide, 2 ml. of concentrated hydrochloric acid and 2 ml. of acetic acid is heated under reflux for 48 hours and, after addition of water, is worked up in the customary manner to give 3-(2' ,4'-difluoro-4-biphenylyl)butyric acid, m.p. 109°-110°.

1. additionA mixture of 1 g
2. temperatureunder reflux for 48 hours