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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 269541Generated: October 25, 2026

Potassium Carbonate → HCID 178478222, compound

https://huagongshe.com/reaction/269541

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant2-Benzyloxy-5-chlorobenzeneboronic acidHCID 4198740—
ReactantToluene ethanolHCID 21863594—
ReactantHCID 178419370HCID 178419370—
CatalystHCID 178418397HCID 178418397—
SolventWaterHCID 962—
SolventDichloromethaneHCID 6344—
ProductHCID 178478222HCID 178478222—

Reaction Steps

A mixture of 5-(2′-bromo-biphenyl-3-yl)-1H-tetrazole (163 mg, 0.54 mmol), 2-benzyloxy-5-chlorobenzeneboronic acid (156 mg, 0.59 mmol), potassium carbonate (589 mg, 4.33 mmol), and tetrakis(triphenylphosphine)palladium(0) (63 mg, 0.05 mmol) in 1.1 toluene/ethanol (5 ml) was stirred and heated under nitrogen for 16 hours. After cooling the mixture was diluted with dichloromethane and water. The organic phase was dried and evaporated.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07446222B2
Source datasetuspto-grants-2008_11
ORD IDord-e093f7ef662441fb9de78c88b9438a19
Source noteuspto-grants-2008_11