Hydrochloric Acid → HCID 9977975, compound

Participants

Reaction Steps

5-Chloro-2-(3-methyl-butoxy)-[1,1′;2′,1″]terphenyl-3″-carboxylic acid ethyl ester (45 mg, 0.106 mmol) and NaOH (excess) were heated at 60° C. in ethanol (3 ml) for 2 hrs. The mixture was then cooled to room temperature, diluted with water, acidified with HCl (1M solution) and extracted with ethyl acetate. The combined extracts were dried (MgSO4) and evaporated to yield the title compound (41 mg, 98%) as a white solid.

Provenance & Evidence