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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 269574Generated: October 29, 2026

2'-Bromo-2-{[(4-fluorophenyl)methyl]oxy}-5-(trifluoromethyl)biphenyl → [2'-{[(4-Fluorophenyl)methyl]oxy}-5'-(trifluoromethyl)-2-biphenylyl]boronic acid

https://huagongshe.com/reaction/269574

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2'-Bromo-2-{[(4-fluorophenyl)methyl]oxy}-5-(trifluoromethyl)biphenylHCID 69310959—
Reactant{5'-Chloro-2'-[(phenylmethyl)oxy]-2-biphenylyl}boronic acidHCID 69312320—
Product[2'-{[(4-Fluorophenyl)methyl]oxy}-5'-(trifluoromethyl)-2-biphenylyl]boronic acidHCID 69310930—

Reaction Steps

Prepared as for {5′-chloro-2′-[(phenylmethyl)oxy]-2-biphenylyl}boronic acid but using 2′-bromo-2-{[(4-fluorophenyl)methyl]oxy}-5-(trifluoromethyl)biphenyl instead of 2′-bromo-5-chloro-2-[(phenylmethyl)oxy]biphenyl. LC/MS t=3.63, [MH−] 389.0

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07446222B2
Source datasetuspto-grants-2008_11
ORD IDord-b6d0186af34748df905e55d9c70488cb
Source noteuspto-grants-2008_11