benzyl{(1S)-3-[(tert-butoxycarbonyl)amino]-1-[({3-[(tert-butoxycarbonyl)amino]-2-hydroxypropyl}amino)carbonyl]propyl}carbamate → Tert-butyl[3-({(2s)-2-amino-4-[(tert-butoxycarbonyl)amino]butanoyl}amino)-2-hydroxypropyl]carbamate

Participants

Reaction Steps

38 mg (0.12 mmol) of the compound from Example 98A are dissolved in 10 ml of methanol, and 10 mg of palladium on activated carbon (10%) are added. The mixture is hydrogenated under atmospheric pressure for 2 h and filtered through kieselguhr, and the mother liquor is concentrated in vacuo.

Provenance & Evidence