Hydrochloric Acid → HCID 178479349, compound

Participants

Reaction Steps

A mixture of 334 mg (0.417 mmol) of benzyl (2-{[N5-[{[(benzyloxy)carbonyl]amino}(imino)methyl]-N2-(tert-butoxycarbonyl)-L-ornithyl]amino}ethyl)carbamate (Example 102A) and 17 ml of a 4M solution of hydrogen chloride in dioxane is stirred at RT for 4 h. The reaction solution is concentrated, coevaporated with dichloromethane several times, and dried under high vacuum. The crude product is reacted without further purification.

Provenance & Evidence