反应详情

8 ml of a 4M solution of hydrogen chloride in dioxane are added to a solution of 320 mg (0.287 mmol) of benzyl[2-({(3S)-3-{[(benzyloxy)carbonyl]amino}-6-[(tert-butoxycarbonyl)amino]hexanoyl}amino)ethyl]carbamate (Example 104A) in 2 ml of dioxane at 0° C. After 1 h at RT, the reaction solution is concentrated in vacuo, coevaporated with dichloromethane several times and dried under high vacuum. The crude product is reacted without further purification.

1. concentrationthe reaction solution is concentrated in vacuo
2. customdried under high vacuum
3. customThe crude product is reacted without further purification