Hydrochloric Acid → HCID 69218480, compound

Participants

Reaction Steps

A mixture of 270 mg (0.511 mmol) of benzyl-[2-({(2S)-4-{[(benzyloxy)carbonyl]amino}-2-[(tert-butoxycarbonyl)amino]butanoyl}amino)ethyl]carbamate (Example 110A) and 9 ml of a 4M solution of hydrogen chloride in dioxane is stirred at RT for 2 h. The reaction solution is concentrated, coevaporated with dichloromethane several times and dried under high vacuum. The crude product is reacted without further purification.

Provenance & Evidence