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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 269645Generated: October 31, 2026

Hydrochloric Acid → N5-[(Benzyloxy)carbonyl]-L-ornithyl-N5-[(benzyloxy)carbonyl]-N-(2-{[(benzyloxy)carbonyl]amino}ethyl)-L-ornithinamide hydrochloride

https://huagongshe.com/reaction/269645

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantN5-[(Benzyloxy)carbonyl]-N2-(tert-butoxycarbonyl)-L-ornithyl-N5-[(benzyloxy)carbonyl]-N-(2-{[(benzyloxy)carbonyl]amino}ethyl)-L-ornithinamideHCID 86619431—
Solvent1,4-DioxaneHCID 31275—
ProductN5-[(Benzyloxy)carbonyl]-L-ornithyl-N5-[(benzyloxy)carbonyl]-N-(2-{[(benzyloxy)carbonyl]amino}ethyl)-L-ornithinamide hydrochlorideHCID 86619432—

Reaction Steps

Preparation takes place in analogy to Example 122A from 70 mg (0.09 mmol) of N5-[(benzyloxy)carbonyl]-N2-(tert-butoxycarbonyl)-L-ornithyl-N5-[(benzyloxy)carbonyl]-N-(2-{[(benzyloxy)carbonyl]amino}ethyl)-L-ornithinamide (Example 123A) in 0.68 ml of a 4M solution of hydrogen chloride in dioxane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07446102B2
Source datasetuspto-grants-2008_11
ORD IDord-3e5372c8bd6c4e9b84fa1b9beaaf0e0a
Source noteuspto-grants-2008_11