Hydrochloric Acid → HCID 50939316, compound

Participants

Reaction Steps

7 mg (0.008 mmol) of tert-butyl{3-[(8S,11S,14S)-8-{[((1S)-4-amino-1-{[((1S)-3-amino-1-{[(2-aminoethyl)amino]carbonyl}propyl)amino]carbonyl}butyl)amino]carbonyl}-14-[(tert-butoxycarbonyl)amino]-5,17-dihydroxy-10,13-dioxo-9,12-diazatricyclo[14.3.1.12,6]henicosa-1(20),2(21),3,5,16,18-hexaen-11-yl]propyl}carbamate tris(hydroacetate) (Example 208A) are added into 0.6 ml of a 4N solution of hydrogen chloride in dioxane and stirred at RT for 30 min. The reaction solution is concentrated, coevaporated with dichloromethane several times and dried under high vacuum.

Provenance & Evidence