HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 23071583, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | N-(4-nitrophenyl)morpholine-4-carboxamide | HCID 332214 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 23071583 | HCID 23071583 | — |
Reaction Steps
N-methylation of N-(4-nitrophenyl)morpholine-4-carboxamide was effected by allowing it to react with sodium hydride and methyl iodide in DMF, and the resulting compound was subjected to catalytic hydrogenation in the same manner as shown in Reference Example 3 to obtain N-(4-aminophenyl)-N-methylmorpholine-4-carboxamide. F: 236.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449456B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-6aec195e3c744350a6d739f69e0dabd2 |
| Source note | uspto-grants-2008_11 |