Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Fluoro-4-nitrotoluene → 2-(4-Amino-2-fluorophenyl)ethanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Fluoro-4-nitrotoluene | HCID 74025 | — |
| 반응물 | Sodium Methoxide | HCID 10942334 | — |
| 용매 | Dimethyl Sulfoxide | HCID 679 | — |
| 생성물 | 2-(4-Amino-2-fluorophenyl)ethanol | HCID 45090600 | — |
반응 단계
2-Fluoro-4-nitrotoluene and p-formaldehyde were allowed to undergo the reaction in DMSO in the presence of sodium methoxide, and then the resulting compound was subjected to catalytic hydrogenation in the same manner as shown in Reference Example 3 to obtain 3-fluoro-4-(2-hydroxyethyl)aniline. F: 156.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07449456B2 |
| 출처 데이터셋 | uspto-grants-2008_11 |
| ORD ID | ord-a0076cd7d98346488810ae7fab1d0183 |
| 출처 메모 | uspto-grants-2008_11 |