HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23111457, compound → HCID 23111417, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23111457 | HCID 23111457 | — |
| Reactant | 1-(4-Methoxy-3-methylphenyl)-4-phenethylpiperazine | HCID 23111510 | — |
| Product | HCID 23111417 | HCID 23111417 | 44.6% |
Reaction Steps
Production Example 10 was repeated except that 1-(4-methoxy-3-methylphenyl)-4-phenethylpiperazine was replaced with 5-methoxy-2-(4-phenylpiperidino)benzonitrile (99 mg), and the resulting crude product was purified on TLC (developer, hexane: ethyl acetate=2:1) to provide 5-hydroxy-2-(4-phenylpiperidino)benzonitrile (42 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449466B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-ae4e50c17d334b54a60db97c06bf3c3c |
| Source note | uspto-grants-2008_11 |