HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23111430, compound → HCID 23111397, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23111430 | HCID 23111430 | — |
| Reactant | 1-(4-Methoxy-3-methylphenyl)-4-phenethylpiperazine | HCID 23111510 | — |
| Product | HCID 23111397 | HCID 23111397 | 42.3% |
Reaction Steps
Production Example 10 was repeated except that 1-(4-methoxy-3-methylphenyl)-4-phenethylpiperazine was replaced with 2-(4-benzylpiperidino)-5-methoxybenzonitrile (99 mg), and the resulting crude product was purified on TLC (developer, hexane: ethyl acetate=2:1) to provide 2-(4-benzylpiperidino)-5-hydroxy-benzonitrile (40 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449466B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-9d0280122f1e4213bf78edaf4549acb4 |
| Source note | uspto-grants-2008_11 |