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HRID269888

反应详情

EQUATION

反应方程式

HRID 269888 的结构方程式

REACTANTS

反应物

2
结构：Clc1cc(N2CCN(CCCC3CCCCC3)CC2)ccc1OCc1ccccc1
HCID23111408

未命名化合物

结构：Clc1cc(OCc2ccccc2)ccc1N1CCN(CCc2ccccc2)CC1
HCID23111462

未命名化合物

PRODUCTS

生成物

1
结构：Oc1ccc(N2CCN(CCc3ccccc3)CC2)c(Cl)c1
HCID23111423

未命名化合物

收率 57.3%

PROCEDURE

实验过程

Production Example 30 was repeated except that 1-(4-benzyloxy-3-chlorophenyl)-4-(3-cyclohexylpropyl)piperazine was replaced with 1-(4-benzyloxy-2-chlorophenyl)-4-phenethylpiperazine (65 mg). Thus obtained crude product was purified on TLC (developer, chloroform: methanol=17:1) to provide 3-chloro-4-(4-phenethylpiperazin-1-yl)phenol (29 mg).

WORKUP

后处理

  1. customThus obtained crude product
  2. customwas purified on TLC (developer, chloroform: methanol=17:1)