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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 269891Generated: October 31, 2026

HCID 23111502, compound → HCID 86607272, compound

https://huagongshe.com/reaction/269891

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 23111502HCID 23111502—
Reactant1-(4-Methoxy-3-methylphenyl)-4-phenethylpiperazineHCID 23111510—
ProductHCID 86607272HCID 86607272—

Reaction Steps

Production Example 10 was repeated except that 1-(4-methoxy-3-methylphenyl)-4-phenethylpiperazine was replaced with 1-(2-cyclohexylethyl)-4-(3-fluoro-4-methoxyphenyl)piperazine (218 mg) and the resulting crude product was purified on TLC (developer, chloroform: methanol=18:1) to provide 4-[4-(2-cyclohexylethyl-piperazin-1-yl]-2-fluorophenol (77 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07449466B2
Source datasetuspto-grants-2008_11
ORD IDord-ada700e9bb9b494fbefc1226b239aefd
Source noteuspto-grants-2008_11