HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23111491, compound → HCID 23111412, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23111491 | HCID 23111491 | — |
| Reactant | 1-(4-Methoxy-3-methylphenyl)-4-phenethylpiperazine | HCID 23111510 | — |
| Product | HCID 23111412 | HCID 23111412 | 38% |
Reaction Steps
Production Example 10 was repeated except that 1-(4-methoxy-3-methylphenyl)-4-phenethylpiperazine was replaced with 1-(3-fluoro-4-methoxyphenyl)-4-phenethylpiperazine (482 mg), and the resulting crude product was purified on TLC (developer, chloroform: methanol=17:1) to provide 2-fluoro-4-(4-phenethylpiperazin-1-yl)phenol (175 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449466B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-b7ee3e8edcef4ad3a1c4ff6670254ad3 |
| Source note | uspto-grants-2008_11 |