HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23111451, compound → HCID 23111436, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23111451 | HCID 23111451 | — |
| Reactant | 1-(4-Methoxy-3-methylphenyl)-4-phenethylpiperazine | HCID 23111510 | — |
| Product | HCID 23111436 | HCID 23111436 | 50.8% |
Reaction Steps
Production Example 10 was repeated except that 1-(4-methoxy-3-methylphenyl)-4-phenethylpiperazine was replaced with 1-(2-fluoro-4-methoxyphenyl)-4-phenethylpiperazine (367 mg), and the resulting crude product was purified on TLC (developer, chloroform: methanol=17:1) to provide 3-fluoro-4-(4-phenethyl-piperazin-1-yl)phenol (178 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449466B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-a8646fb48410429faeb5da8ed5596706 |
| Source note | uspto-grants-2008_11 |