反应详情

Production Example 10 was repeated except that 1-(4-methoxy-3-methylphenyl)-4-phenethylpiperazine was replaced with 1-(2,5-difluoro-4-methoxyphenyl)-4-(3-phenylpropyl)piperidine (230 mg). The resulting crude product was purified on TLC (developer, hexane: ethyl acetate=3:1) to provide 2,5-difluoro-4-[4-(3-phenylpropyl)piperidino]phenol (71 mg).

1. customThe resulting crude product was purified on TLC (developer, hexane: ethyl acetate=3:1)