HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Methoxyphenyl)-4-phenethylpiperazine → HCID 23111459, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Methoxyphenyl)-4-phenethylpiperazine | HCID 15527076 | — |
| Reactant | HCID 23111422 | HCID 23111422 | — |
| Product | HCID 23111459 | HCID 23111459 | 45.7% |
Reaction Steps
Production Example 2 was repeated except that 1-(4-methoxyphenyl)-4-phenethylpiperazine was replaced with 1-[1-(2,5-difluoro-4-methoxyphenyl)-4-piperidylcarbonyl]piperidine (406 mg). The resulting crude product was purified on TLC (developer, chloroform: methanol=12:1) to provide 1-[1-(2,5-difluoro-4-hydroxyphenyl)-4-piperidylcarbonyl]piperidine (178 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449466B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-14fe77fad58b48309cb6e0ffdbfe3d62 |
| Source note | uspto-grants-2008_11 |