反应详情

Production Example 10 was repeated except that 1-(4-methoxy-3-methylphenyl)-4-phenethylpiperazine was replaced with 1-(4-cyclohexylbutyl)-4-(2,5-difluoro-4-methoxyphenyl)-piperazine (482 mg). The resulting crude product was purified on TLC (developer, chloroform: methanol=16:1) to provide 4-[4-(4-cyclohexylbutyl)piperazin-1-yl]-2,5-difluorophenol (128 mg).

1. customThe resulting crude product was purified on TLC (developer, chloroform: methanol=16:1)