HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 23111449, compound → HCID 23111511, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 23111449 | HCID 23111449 | — |
| Reactant | 1-(4-Methoxy-3-methylphenyl)-4-phenethylpiperazine | HCID 23111510 | — |
| Product | HCID 23111511 | HCID 23111511 | 27.6% |
Reaction Steps
Production Example 10 was repeated except that 1-(4-methoxy-3-methylphenyl)-4-phenethylpiperazine was replaced with 1-(4-cyclohexylbutyl)-4-(2,5-difluoro-4-methoxyphenyl)-piperazine (482 mg). The resulting crude product was purified on TLC (developer, chloroform: methanol=16:1) to provide 4-[4-(4-cyclohexylbutyl)piperazin-1-yl]-2,5-difluorophenol (128 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449466B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-0da9c2c84e8347d3a524f38364565321 |
| Source note | uspto-grants-2008_11 |