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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 269939Generated: October 30, 2026

Benzenepropanoyl chloride → HCID 23111458, compound

https://huagongshe.com/reaction/269939

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenepropanoyl chlorideHCID 64801—
ReactantIsovaleryl chlorideHCID 66054—
Reactant1-(4-Methoxyphenyl)-piperazine, dihydrochlorideHCID 2723700—
Reactant1-(2,5-Difluoro-4-methoxyphenyl)piperazineHCID 23111492—
ProductHCID 23111458HCID 23111458—

Reaction Steps

Production Example 3 was repeated except that 1-(4-methoxyphenyl)piperazine dihydrochloride and isovaleryl chloride were replaced with 1-(2,5-difluoro-4-methoxyphenyl)-piperazine (228 mg) and 3-phenylpropionyl chloride (178 μL), respectively, to provide crude 4-(2,5-difluoro-4-methoxyphenyl)-1-(3-phenylpropanoyl)piperazine (348 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07449466B2
Source datasetuspto-grants-2008_11
ORD IDord-c2ecd94126c44f9fbea11a4e4ead2f25
Source noteuspto-grants-2008_11