反应详情

Production Example 2 was repeated except that 1-(4-methoxyphenyl)-4-phenethylpiperazine was replaced with 4-(2,5-difluoro-4-methoxyphenyl)-1-(3-phenylpropanoyl)piperazine (344 mg). The resulting crude product was purified on TLC (developer, chloroform: methanol=15:1) to provide 4-(2,5-difluoro-4-hydroxyphenyl)-1-(3-phenylpropanoyl)piperazine (247 mg).

1. customThe resulting crude product was purified on TLC (developer, chloroform: methanol=15:1)