HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Methoxyphenyl)-4-phenethylpiperazine → HCID 23111503, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Methoxyphenyl)-4-phenethylpiperazine | HCID 15527076 | — |
| Reactant | HCID 23111458 | HCID 23111458 | — |
| Product | HCID 23111503 | HCID 23111503 | 74.7% |
Reaction Steps
Production Example 2 was repeated except that 1-(4-methoxyphenyl)-4-phenethylpiperazine was replaced with 4-(2,5-difluoro-4-methoxyphenyl)-1-(3-phenylpropanoyl)piperazine (344 mg). The resulting crude product was purified on TLC (developer, chloroform: methanol=15:1) to provide 4-(2,5-difluoro-4-hydroxyphenyl)-1-(3-phenylpropanoyl)piperazine (247 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449466B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-8cf27458cbff4b949ec43ffd4443da20 |
| Source note | uspto-grants-2008_11 |