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HRID269943

反应详情

EQUATION

反应方程式

HRID 269943 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc(N2CCN(CCc3ccccc3)CC2)cc1
HCID15527076

未命名化合物

结构：CCCCCCCCS(=O)(=O)N1CCN(c2cc(F)c(OC)cc2F)CC1
HCID23111477

未命名化合物

PRODUCTS

生成物

1
结构：CCCCCCCCS(=O)(=O)N1CCN(c2cc(F)c(O)cc2F)CC1
HCID23111452

未命名化合物

收率 87.4%

PROCEDURE

实验过程

Production Example 2 was repeated except that 1-(4-methoxyphenyl)-4-phenethylpiperazine was replaced with 4-(2,5-difluoro-4-methoxyphenyl)-1-(octylsulfonyl)piperazine (300 mg). The resulting crude product was purified on TLC (developer, hexane: ethyl acetate=11:5) to provide 4-(2,5-difluoro-4-hydroxyphenyl)-1-(octylsulfonyl)piperazine (253 mg).

WORKUP

后处理

  1. customThe resulting crude product was purified on TLC (developer, hexane: ethyl acetate=11:5)