反应详情

Production Example 2 was repeated except that 1-(4-methoxyphenyl)-4-phenethylpiperazine was replaced with 4-(2,5-difluoro-4-methoxyphenyl)-1-(4-fluorophenylsulfonyl)-piperazine (300 mg). The resulting crude product was purified on TLC (developer, hexane: ethyl acetate=2:1) to provide 4-(2,5-difluoro-4-hydroxyphenyl)-1-(4-fluorophenylsulfonyl)-piperazine (211 mg).

1. customThe resulting crude product was purified on TLC (developer, hexane: ethyl acetate=2:1)