HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Methoxyphenyl)-4-phenethylpiperazine → HCID 23111481, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Methoxyphenyl)-4-phenethylpiperazine | HCID 15527076 | — |
| Reactant | 4-(2,5-Difluoro-4-methoxyphenyl)-1-(4-fluorophenylsulfonyl)-piperazine | HCID 23111473 | — |
| Product | HCID 23111481 | HCID 23111481 | 73% |
Reaction Steps
Production Example 2 was repeated except that 1-(4-methoxyphenyl)-4-phenethylpiperazine was replaced with 4-(2,5-difluoro-4-methoxyphenyl)-1-(4-fluorophenylsulfonyl)-piperazine (300 mg). The resulting crude product was purified on TLC (developer, hexane: ethyl acetate=2:1) to provide 4-(2,5-difluoro-4-hydroxyphenyl)-1-(4-fluorophenylsulfonyl)-piperazine (211 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449466B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-f921ac9dd4c246fa856463f4a768ccea |
| Source note | uspto-grants-2008_11 |