HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Methoxyphenyl)-4-phenethylpiperazine → HCID 23111495, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Methoxyphenyl)-4-phenethylpiperazine | HCID 15527076 | — |
| Reactant | HCID 23111398 | HCID 23111398 | — |
| Product | HCID 23111495 | HCID 23111495 | 88.1% |
Reaction Steps
Production Example 2 was repeated except that 1-(4-methoxyphenyl)-4-phenethylpiperazine was replaced with 1-(4-chlorobenzenesulfonyl)-4-(2,5-difluoro-4-methoxyphenyl)-piperazine (395 mg). The resulting crude product was purified on silica gel column chromatography (eluent, hexane: ethyl acetate=2:1) to provide 1-(4-chlorophenylsulfonyl)-4-(2,5-difluorophenyl)-piperazine (322 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449466B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-307e24b86e874da688423a30204e0704 |
| Source note | uspto-grants-2008_11 |