HuagongsheHuagongshe Chemistry Print Report · For research reference only
1'-Benzyl-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one → HCID 68959958, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1'-Benzyl-5-fluoro-3H-spiro[2-benzofuran-1,4'-piperidin]-3-one | HCID 67377897 | — |
| Reactant | [1-Benzyl-4-(2-fluorobenzyl)piperidin-4-yl)methanol | HCID 68961767 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 68959958 | HCID 68959958 | 77.5% |
Reaction Steps
This reaction was performed as described for (ii) above using 1′-benzyl-5-fluoro-3H-spiro[2-benzofuran-1,4′-piperidin]-3-one (200 mg, 0.642 mmol), borane THF complex 1M solution (1.34 mL, 1.34 mmol) and THF (3 mL) to give the sub-titled compound (148 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07449475B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-5f269ca04b4045c2a6e89ce237e5ede7 |
| Source note | uspto-grants-2008_11 |