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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 270065Generated: October 26, 2026

Cyclopropylamine → HCID 28390698, compound

https://huagongshe.com/reaction/270065

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropylamineHCID 69828—
ReactantMethyl 4-methoxysalicylateHCID 79523—
ProductHCID 28390698HCID 28390698—

Reaction Steps

A suspension of methyl 2-hydroxy-4-methoxybenzoate (5.1 g, 28.0 mmol) in cyclopropyl amine 24 mL) was stirred at room temperature for 5 days. The volatiles were removed in vacuo and the residue was purified by silica gel flash chromatography (0-60% ethyl acetate in petroleum ether) to give the subtitled compound (1.8 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07449475B2
Source datasetuspto-grants-2008_11
ORD IDord-28b3b4d48a0f4850b7c740c5ce9c9a29
Source noteuspto-grants-2008_11