Diethylamine → {4-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yloxy]-butyl}-diethyl-amine

HRID 270308Notes

Reaction equation

HRID 270308 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:22]=[CH:21][C:10]2[C:11]([C:14]3[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=3)=[N:12][S:13][C:9]=2[CH:8]=1.[CH2:23]([NH:25][CH2:26][CH3:27])[CH3:24]>>[Cl:20][C:17]1[CH:18]=[CH:19][C:14]([C:11]2[C:10]3[CH:21]=[CH:22][C:7]([O:6][CH2:5][CH2:4][CH2:3][CH2:2][N:25]([CH2:26][CH3:27])[CH2:23][CH3:24])=[CH:8][C:9]=3[S:13][N:12]=2)=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 8021DiethylamineHCID 223139036-(4-Bromo-butoxy)-3-(4-chloro-phenyl)-benzo[d]isothiazole

Product 1

HCID 22313971{4-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yloxy]-butyl}-diethyl-amine

Procedure

According to the method in example 7, 6-(4-Bromo-butoxy)-3-(4-chloro-phenyl)-benzo[d]isothiazole and Diethylamine were converted to yield {4-[3-(4-Chloro-phenyl)-benzo[d]isothiazol-6-yloxy]-butyl}-diethyl-amine, MS: 389 (MH+, 1Cl).

Sources & evidence

ORD record
ord-bc48e5cbd32d4a3193216a2a636dfd99
Source dataset
uspto-grants-2008_11
Patent number
US07449483B2

Reaction notes

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