Piperidine → HCID 22314107, compound

HRID 270317Notes

Reaction equation

HRID 270317 reaction equation
Br[CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]1[CH:27]=[CH:26][C:10]2[C:11]([C:16]3[CH:21]=[CH:20][C:19]([C:22]([F:25])([F:24])[F:23])=[CH:18][CH:17]=3)=[N:12][S:13](=[O:15])(=[O:14])[C:9]=2[CH:8]=1.[NH:28]1[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1>>[N:28]1([CH2:2][CH2:3][CH2:4][CH2:5][O:6][C:7]2[CH:27]=[CH:26][C:10]3[C:11]([C:16]4[CH:21]=[CH:20][C:19]([C:22]([F:25])([F:24])[F:23])=[CH:18][CH:17]=4)=[N:12][S:13](=[O:15])(=[O:14])[C:9]=3[CH:8]=2)[CH2:33][CH2:32][CH2:31][CH2:30][CH2:29]1

Participants

3

Reactant 2

HCID 8082PiperidineHCID 22313972HCID 22313972, compound

Product 1

HCID 22314107HCID 22314107, compound

Procedure

According to the method in example 10, 6-(4-Bromo-butoxy)-3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazole 1,1-dioxide and Piperidine were converted to yield 6-(4-Piperidin-1-yl-butoxy)-3-(4-trifluoromethyl-phenyl)-benzo[d]isothiazole 1,1-dioxide, MS: 467 (MH+).

Sources & evidence

ORD record
ord-1db7e4aa3d1d4f889d4413380d320f88
Source dataset
uspto-grants-2008_11
Patent number
US07449483B2

Reaction notes

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