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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 270402Generated: October 26, 2026

2-(Methylamino)ethanol → 2-({3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-methyl-amino)-ethanol

https://huagongshe.com/reaction/270402

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Methylamino)ethanolHCID 8016—
Reactant6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiopheneHCID 22314034—
Product2-({3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-methyl-amino)-ethanolHCID 22314118—

Reaction Steps

In analogy to example 3.1, 6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene and 2-(methylamino)ethanol were converted to yield 2-({3-[3-(4-Fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-methyl-amino)-ethanol as colorless oil, MS: 360 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07449483B2
Source datasetuspto-grants-2008_11
ORD IDord-d8afa53f6422499a917e61c1e8e2bbe2
Source noteuspto-grants-2008_11