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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 270404Generated: October 29, 2026

2-(Ethylamino)ethanol → 2-(Ethyl-{3-[3-(4-fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-amino)-ethanol

https://huagongshe.com/reaction/270404

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Ethylamino)ethanolHCID 8072—
Reactant6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiopheneHCID 22314034—
Product2-(Ethyl-{3-[3-(4-fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-amino)-ethanolHCID 22314094—

Reaction Steps

In analogy to example 3.1, 6-(3-Bromo-propoxy)-3-(4-fluoro-phenyl)-benzo[b]thiophene and 2-(ethylamino)ethanol were converted to yield 2-(Ethyl-{3-[3-(4-fluoro-phenyl)-benzo[b]thiophen-6-yloxy]-propyl}-amino)-ethanol as colorless oil, MS: 374 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07449483B2
Source datasetuspto-grants-2008_11
ORD IDord-0528bfd8b9c04e1bbf84fd37147b185e
Source noteuspto-grants-2008_11