Chlorosuccinimide → 4-Chloro-3-ethyl-5-(trifluoromethyl)-1H-Pyrazole

HRID 270795Notes

Reaction equation

HRID 270795 reaction equation

[CH2:1]([C:3]1[NH:7][N:6]=[C:5]([C:8]([F:11])([F:10])[F:9])[CH:4]=1)[CH3:2].C1C(=O)N([Cl:19])C(=O)C1>CC#N>[Cl:19][C:4]1[C:5]([C:8]([F:10])([F:11])[F:9])=[N:6][NH:7][C:3]=1[CH2:1][CH3:2]

Participants

4

Reactant 2

HCID 31398Chlorosuccinimide

HCID 230062095-ethyl-3-(trifluoromethyl)-1H-pyrazole

Product 1

HCID 210711484-Chloro-3-ethyl-5-(trifluoromethyl)-1H-Pyrazole

Reagents, catalysts & solvents 1

HCID 6342AcetonitrileSolvent

Procedure

Following protocol L, 5-ethyl-3-trifluoromethyl-1H-pyrazole was treated with NCS in CH3CN to yield title compound

Sources & evidence

ORD record: ord-f5ad455cd4914cf885c79850cb2f8fcd
Source dataset: uspto-grants-2008_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07449576B1

Reaction notes

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