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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 271087Generated: October 31, 2026

Hydrochloric Acid → HCID 178428975, compound

https://huagongshe.com/reaction/271087

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant4-[6-(2,4-difluoro-phenoxy)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-3-methyl-phenolHCID 136066602—
ProductHCID 178428975HCID 178428975—

Reaction Steps

4-[6-(2,4-Difluoro-phenoxy)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-3-methyl-phenol was treated with HCl using the procedure described in step 8 of Example 11 to afford 0.20 g of 4-[6-(2,4-difluoro-phenoxy)-1H-pyrazolo[3,4-d]pyrimidin-3-yl]-3-methyl-phenol. Mass Spec. M+H=355.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07452880B2
Source datasetuspto-grants-2008_11
ORD IDord-78aa2d7ec8c54b1ca0633e59dda921ef
Source noteuspto-grants-2008_11