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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 271262Generated: November 1, 2026

Sodium Hydroxide → HCID 59834998, compound

https://huagongshe.com/reaction/271262

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantTetrabutylammonium FluorideHCID 2724141—
ReactantHCID 59835002HCID 59835002—
SolventMethanolHCID 887—
SolventWaterHCID 962—
ProductHCID 59834998HCID 5983499872.1%

Reaction Steps

A solution of ethyl 2-amino-6-(2-furyl)-9H-purine-9-acetate (200 mg, 0.69 mmol) in MeOH (3 mL) was treated with aq NaOH (2-M, 0.5 mL, 1 mmol), refluxed for 10 min, cooled, diluted with water, acidified with aq HCl (1-M) and the resulting solid filtered, washed with water and dried to give the title compound (129 mg, 72%) as a yellow solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07452894B2
Source datasetuspto-grants-2008_11
ORD IDord-dd13ad71030e4083a0cbcf23820a6b8d
Source noteuspto-grants-2008_11