反应详情

To a solution of 0.47 g of trans-[4-(4-phenyl-but-1-enyl)-cyclohexyl]-carbamic acid tert-butyl ester in 4 mL of dichloromethane at 0° C. and under nitrogen was added 2 mL of trifluoroacetic acid. The reaction was aged for 1 hour, concentrated under reduced pressure. The resulting oil dissolved in methylene chloride and concentrated to give an oil which was utilized in the next step without purification: LCMS (M+1)=230.

1. concentrationconcentrated under reduced pressure
2. dissolutionThe resulting oil dissolved in methylene chloride
3. concentrationconcentrated
4. customto give an oil which
5. customwas utilized in the next step without purification