Piperazine → HCID 136341917, compound

HRID 271533Notes

Reaction equation

HRID 271533 reaction equation
[N:1]1([CH2:7][C:8]([N:10]2[CH2:15][CH2:14][CH:13]([C:16]3[O:20][C:19]([C:21]4[CH:22]=[C:23]5[C:27](=[CH:28][CH:29]=4)[C:26](=[N:30][OH:31])[CH2:25][CH2:24]5)=[C:18]([C:32]4[CH:37]=[CH:36][N:35]=[CH:34][CH:33]=4)[CH:17]=3)[CH2:12][CH2:11]2)=[O:9])[CH2:6][CH2:5]O[CH2:3][CH2:2]1.[NH:38]1CCNCC1>>[N:1]1([CH2:7][C:8]([N:10]2[CH2:11][CH2:12][CH:13]([C:16]3[O:20][C:19]([C:21]4[CH:22]=[C:23]5[C:27](=[CH:28][CH:29]=4)[C:26](=[N:30][OH:31])[CH2:25][CH2:24]5)=[C:18]([C:32]4[CH:33]=[CH:34][N:35]=[CH:36][CH:37]=4)[CH:17]=3)[CH2:14][CH2:15]2)=[O:9])[CH2:6][CH2:5][NH:38][CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 4837PiperazineHCID 136341918HCID 136341918, compound

Product 1

HCID 136341917HCID 136341917, compoundYield 17%

Procedure

The title compound (0.047 g, 17%) was prepared from the product of Example 47 Step 1 and piperazine using the method of Example 47 Step 2; MS(ES+) m/e 485 [M+H]+.

Sources & evidence

ORD record
ord-8bde615d390f403e89b78747ab4a97ee
Source dataset
uspto-grants-2008_11
Patent number
US07452906B2

Reaction notes

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