HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Oxalate → HCID 59836313, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Oxalate | HCID 7268 | — |
| Reactant | 1,4-Dioxaspiro[4.5]decan-8-one | HCID 567415 | — |
| Reactant | Lithium Hexamethyldisilazide | HCID 2733832 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 59836313 | HCID 59836313 | — |
Reaction Steps
According to the procedure of Example 2, a solution of 1,4-dioxaspiro[4.5]decane-8-one Compound 22a in ether was added to a solution of LHMDS in ether at −78° C. The diethyloxalate Compound 2b was added to the mixture and reacted to produce an oxo-(8-oxo-1,4-dioxa-spiro[4.5]dec-7-yl)-acetic acid ethyl ester Compound 22b.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07452997B2 |
| Source dataset | uspto-grants-2008_11 |
| ORD ID | ord-333723045d2b47c6adc401a9ef4f32e5 |
| Source note | uspto-grants-2008_11 |