反应详情

A mixture as 33.7 g (0.106 mole) of 1-(2,6-dichlorophenyl-N-methylamidino)-3-(t-butyl)urea and 200 ml of conc. hydrochloric acid is refluxed for 1/2 hour. The reaction mixture is cooled, filtered and washed with 10 ml of 1:1 HCl/H2O and dried. The product is then recrystallized from ethanol-ether to obtain 1-(2,6-dichlorophenyl-N-methylamidino)urea.

1. temperatureThe reaction mixture is cooled
2. filtrationfiltered
3. washwashed with 10 ml of 1:1 HCl/H2O
4. customdried
5. customThe product is then recrystallized from ethanol-ether