Methyl iodide → 1-(2,6-Dichlorophenyl)-3-carbamyl-3-methylthiouronium iodide

HRID 27203Notes

Reaction equation

HRID 27203 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]([NH:12][C:13](=[O:15])[NH2:14])=[S:11].[I:16][CH3:17]>CO>[I-:16].[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH+:9]=[C:10]([N:12]([C:13](=[O:15])[NH2:14])[CH3:17])[SH:11]

Participants

4

Reactant 2

HCID 6328Methyl iodideHCID 204344241-(2,6-Dichlorophenyl)-3-carbamylthiourea

Product 1

HCID 1784851951-(2,6-Dichlorophenyl)-3-carbamyl-3-methylthiouronium iodide

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

26.4 g (0.1 mole) of 1-(2,6-dichlorophenyl)-3-carbamylthiourea is combined with 200 ml of methanol and 14.1 g (0.1 mole) of iodomethane and refluxed for 4 hours. This is then evaporated to dryness and 100 ml of hexane is added. The mixture is filtered to obtain 1-(2,6-dichlorophenyl)-3-carbamyl-3-methylthiouronium iodide.

Workup

  1. temperaturerefluxed for 4 hours
  2. customThis is then evaporated to dryness and 100 ml of hexane
  3. additionis added
  4. filtrationThe mixture is filtered

Sources & evidence

ORD record
ord-5dd0d1be2a4841c485ed4cea453620ba
Source dataset
uspto-grants-1980_09
Patent number
US04220658

Reaction notes

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