Hydrochloride methanol → Ethyl 3-{(2-aminoacetyl)amino}propionate monohydrochloride

HRID 272061노트

반응식

C(OC([NH:8][CH2:9][C:10]([NH:12][CH2:13][CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])=[O:11])=O)(C)(C)C.[ClH:20].CO>>[ClH:20].[NH2:8][CH2:9][C:10]([NH:12][CH2:13][CH2:14][C:15]([O:17][CH2:18][CH3:19])=[O:16])=[O:11]

참가 물질

반응물 2

HCID 21893726Hydrochloride methanol

HCID 21893946Ethyl 3-(2-{(tert-butoxycarbonyl)amino}acetylamino)propionate

생성물 1

HCID 22647362Ethyl 3-{(2-aminoacetyl)amino}propionate monohydrochloride

실험 절차

2.0 Grams of ethyl 3-(2-{(tert-butoxycarbonyl)amino}-acetylamino)propionate were dissolved in 30 ml of 10% hydrochloric acid-methanol and stirred for 15 hours at room temperature. Upon distilling the reaction liquid off under reduced pressure, 1.52 g of the title compound was obtained.

후처리

distillationUpon distilling
customthe reaction liquid off under reduced pressure

출처 및 근거

ORD 기록: ord-2307c7390744429b96f5f0e1f5769833
출처 데이터셋: uspto-grants-2008_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07452908B2

반응 노트

불러오는 중…