Benzene, (3-chloro-1-propenyl)- → HCID 21961361, compound

HRID 272316Notes

Reaction equation

HRID 272316 reaction equation
[OH:1][C:2]1[CH:7]=[C:6]([CH3:8])[C:5]([NH:9][CH:10]=[O:11])=[C:4]([CH3:12])[C:3]=1[CH3:13].[CH2:14](Cl)[CH:15]=[CH:16][C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>C(OCC)(=O)C.CCCCCC>[CH3:12][C:4]1[C:3]([CH3:13])=[C:2]([O:1][CH2:14]/[CH:15]=[CH:16]/[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)[CH:7]=[C:6]([CH3:8])[C:5]=1[NH:9][CH:10]=[O:11]

Participants

4

Reactant 2

HCID 94242Benzene, (3-chloro-1-propenyl)-HCID 21961295N-(4-hydroxy-2,3,6-trimethylphenyl)formamide

Product 1

HCID 21961361HCID 21961361, compoundYield 44%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

By using N-(4-hydroxy-2,3,6-trimethylphenyl)formamide and cinnamyl chloride, the title compound was synthesized according to Reference Example 17a. Yield: 44%. Melting point: 197-199° C. (Ethyl acetate-hexane)

Sources & evidence

ORD record
ord-6e77de9fed5f479287c7603c78d1f766
Source dataset
uspto-grants-2008_11
Patent number
US07456162B2

Reaction notes

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